https://synstojournals.com/biotech/issue/feed 2025-03-25T07:12:53+00:00 SYNSTO (Rahul Singh) synsto.biotech@gmail.com Open Journal Systems <p><strong>Innovative Research in Biotechnology</strong> is an open-access, peer-reviewed journal which provides an advanced forum for investigations and discussions related to the study and application of biotechnology. The journal publishes research regular research papers, reviews/mini-reviews, and letters in all core areas of biotechnology, including all nearly related areas.</p> <p><span style="text-decoration: underline;"><strong>*Special Offer*</strong><br /></span>* Back year publication cost is Rs 600 for each article and current year Rs 800 for each article.<br />* For Foreign Country publication cost is $20 for each article. </p> https://synstojournals.com/biotech/article/view/151 2025-03-25T07:12:53+00:00 H. Kinjir a@gmail.com Alhagie Drammeh a@gmail.com Fatima B. Tanimu a@gmail.com A. Lawal a@gmail.com H. G. Anchau a@gmail.com J. M. Yelwa a@gmail.com

<p>Diabetes and hypertension are two of the most widespread global chronic diseases with high morbidity and mortality. Both of the diseases have a strong link with metabolic disorders and lipid metabolism dysregulation. In this review, we explore the intricate relationship between lipid profiles and lipid peroxides and antioxidant profiles in the etiology of diabetes and hypertension. Both of the diseases have elevated levels of low-density lipoprotein (LDL) cholesterol and decreased levels of high-density lipoprotein (HDL) cholesterol as a commonality in the causation of cardiovascular complications. In addition, oxidative stress in the form of excessive ROS production and subsequent lipid peroxidation hastens the disease process. Dysfunctional antioxidant defense systems in the body in the context of diabetes and hypertension further highlight the need for antioxidant therapies. Recent evidence suggests that lipid-modulating and antioxidant therapies targeting specific pathways may be the key to novel disease prevention and improved cardiovascular outcomes. This review integrates the importance of dissecting such intricate pathways towards the development of successful management and therapy paradigms in an attempt to improve patient outcome and reduce the health burden of such chronic diseases. In addition, we emphasize gaps in the literature and present directions for the exploration of personalized therapy interventions based on lipid and antioxidant imbalance.</p>

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