The effect of sexual abstinence period on 8-hydroxydesoxyguanosine, nitric oxide and total antioxidant capacity in seminal plasma and semen quality in abnormal semen
Keywords:
total antioxidant capacity, sexual abstinence period (2-3), (4-5) days, 8-hydroxydeoxyguanosine, semen quality, nitric oxide, semenAbstract
Background: This study aimed to evaluate the influence of (2-3), (4-5) days periods of sexual abstinence on semen parameters and on levels of both oxidative stress and antioxidants in seminal plasma of abnormal semen.
Methods: Abnormal semen samples were collected from 47 infertile men and their semen parameters and levels of NO, TAC, 8-OHdG were examined in both periods (2-3) days and (4-5) days.
Results: The results of the current study showed a statistically no significant (p≤0.05) decrease in sperm concentration and normal sperm morphology of a group of (4-5) days compared to the group (2-3) days, and no differences was observed in the curvature of progressive motility, semen volume and pH between the two groups and showed a statistically no significant (p≤0.05) increase in TAC concentration and also a statistically no significant (p≤0.05) decrease in the level of 8-OHdG in the seminal plasma of the abstinence group (4-5) days compared to the abstinence group (2-3) days.
Conclusion: A sexual abstinence periods (2-3) days is appropriate for a patient with abnormal sperm, because an increase in the period of abstinence (4-5) days leads to a decrease in sperm concentration and the percentage of normal sperm morphology, despite the improvement in the level of TAC and 8-OHdG.
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